Perfect Partner

DOUBLE THE PAIN RELIEF WITHOUT THE WORRISOME SIDE EFFECTS AND BAGGAGE^*

Avoid the side effects and baggage associated with pain relief drugs:

Confusion and difficulty concentrating

Risk of addiction

Problems with combining medications

ZTlido cuts your pain levels in half

PAIN LEVELS DROPPED

48%

In a clinical study that lasted 8 weeks, patients who added ZTlido to their daily pain management routine with pregabalin (Lyrica®) said their pain levels dropped 48%.^†

^†ZTlido equivalent.
"ZTlido equivalent" connotes that study was performed using bioequivalent lidocaine 5% patch.

BREAK THE PAIN CYCLE

Better sleep at night so you can do more during the day

How to use

LEARN MORE

Approved Use and Important Safety Information

What is ZTLIDO used for?
ZTLIDO is a prescription medicine used for relief of pain from damaged nerves (neuropathic pain) that follows healing of shingles. It is not known if ZTLIDO is safe and effective in children. A ZTLIDO topical system should only be worn a single time for up to 12 hours within a 24-hour period (12 hours on and 12 hours off).

When should I not use ZTLIDO?
You should not use ZTLIDO if you have had a reaction to lidocaine or other pain products like lidocaine or to any component of the product. Tell your doctor or pharmacist about any allergies to medications.

ZTLIDO may interact with other medications. If you take a medication for an irregular heartbeat or other pain medications, check with your healthcare provider before using ZTLIDO.

What Warnings should I know about ZTLIDO?

Accidental exposure: Used and new ZTLIDO topical systems can cause serious injuries to small children and pets from accidental chewing or swallowing. Keep new and used topical systems out of the reach of children and pets.
Lidocaine overdose: Applying topical systems to an area greater than recommended by your doctor or longer than directed by your doctor can cause side effects. Use ZTLIDO exactly as directed by your healthcare provider. Using ZTLIDO on skin that is cut or scraped or applying heat sources to a ZTLIDO topical system may increase the amount of drug taken into the body and could cause side effects, so only apply to intact skin.
Methemoglobinemia: Local anesthetics may cause methemoglobinemia, a serious condition that must be treated promptly. Stop use of ZTLIDO and seek medical attention immediately if you develop pale, gray, or blue colored skin (cyanosis); headache; rapid heart rate; shortness of breath; lightheadedness; or fatigue.
Application site reactions: Skin reactions where ZTLIDO is applied can occur during or immediately after use.
Contact of ZTLIDO with your eyes: If ZTLIDO comes into contact with your eye, immediately wash out the eye with water or saline and protect the eye until sensation returns.

What should I tell my healthcare provider?
Breastfeeding women should tell their doctor before starting ZTLIDO since the medication is excreted in breast milk. ZTLIDO has not been studied in pregnant women so tell your doctor if you are pregnant or planning to be.

What are the side effects of ZTLIDO?
The most common side effects of ZTLIDO are application site reactions such as irritation, redness, and itching. These are not all of the side effects of ZTLIDO. Talk to your healthcare provider for more information.

What other medications might interact with ZTLIDO?
Certain medications used to treat an irregular heartbeat and certain pain medications called local anesthetics can interact with ZTLIDO. Be sure to tell your healthcare provider about all medications you take.

To report SUSPECTED ADVERSE REACTIONS, contact SCILEX Pharmaceuticals Inc. at 1-866-SCILEX3 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
The risk information provided here is not comprehensive. To learn more, talk about ZTLIDO with your healthcare provider or pharmacist. The FDA-approved product labeling can be found by clicking here or calling 1-866-SCILEX3.